Drugs Name
Generic Name: Jixueganshuang Ointment
Brand Name: Fuyuan
English Name: JiXueGanShuangRuanGao (FuYuan)
Pinyin: Jixueganshuang Ruangao

Ingredients
Main Ingredient: Total Asiaticosides from Centella asiatica

Appearance
This product is a white-like ointment.

Indications
It promotes wound healing. Used for the treatment of external injuries, surgical wounds, burns, keloids, and scleroderma.

Dosage and Administration
For external use. Apply to the affected area, 3-4 times a day.

Adverse Reactions
Not yet clear.

Contraindications
Prohibited for those allergic to this product.

Precautions
Use with caution in pregnant women and those with allergic constitutions.

Special Populations
Pregnancy and Lactation: Use with caution in pregnant women.

Drug Interactions
Not yet clear.

Storage
Store in a shaded, airtight, cool, and dry place.

Specifications
2.5%

Packaging Specifications
20g/tube

Expiration
36 months.

Total Asiaticosides from Centella asiatica

Basic Properties

• Appearance: Total Asiaticosides appear as a light yellow to light brownish powder, odorless, with a slightly bitter taste and slight hygroscopicity.
• Solubility: Easily soluble in water and ethanol, insoluble in chloroform and ether.

Efficacy and Functions

1. Promotion of Wound Healing: Total Asiaticosides exhibit unique dual-regulatory effects in promoting wound repair and inhibiting excessive scar proliferation. They can enhance the function of the reticuloendothelial system, stimulate capillary regeneration, and improve blood circulation, thereby accelerating wound healing.
2. Anti-inflammatory Effects: Total Asiaticosides exert their anti-inflammatory effects by inhibiting the production of cytokines such as TNF-α and IL-6, helping to reduce inflammatory responses and redness/swelling symptoms.
3. Antioxidant Properties: Total Asiaticosides also show antioxidant activity, helping to resist damage from free radicals and protect skin cells from oxidative stress.
4. Improvement of Skin Disease Symptoms: Products containing Total Asiaticosides can improve symptoms of skin diseases such as acne and eczema, including redness, itching, and scaling.

Clinical Applications

Total Asiaticosides are commonly used clinically in the treatment of:

• Traumatic injuries, including surgical incisions, cesarean sections, skin grafting, and other wounds.
• Burns, including burns of various degrees, scalds, chemical burns, and sunburns.
• Keloids and scleroderma, by regulating the activity and proliferation cycle of fibroblasts, inhibiting excessive proliferation of scar fibroblasts, reducing fibrosis, and making collagen fibers relatively regular and parallel, thus inhibiting disorderly scar proliferation.

Precautions

• Pregnant women and individuals with allergic constitutions should use Total Asiaticosides with caution and consult a doctor before use.
• Patients allergic to Total Asiaticosides should avoid using them.
• The adverse reactions of Total Asiaticosides are not yet clear. If used concurrently with other medications, drug interactions may occur. Consult a physician or pharmacist beforehand.