双环醇片 Shuanghuanchun Pian, Bicyclol Tablets, for Elevated Aminotransferase Levels Due to Chronic Hepatitis

Drug Name
Bicyclol Tablets
Shuanghuanchun Pian

Ingredients
The main ingredient of this product is bicyclol.

Properties
This product is white tablets.

Indications
This product is indicated for the treatment of elevated aminotransferase levels caused by chronic hepatitis.

Dosage and Administration
For oral administration, the usual adult dose is 25mg (1 tablet) each time. If necessary, the dose can be increased to 50mg (2 tablets). Take three times a day for at least 6 months or as directed by your physician. Gradual dose reduction should be applied.

Adverse Reactions
After taking this medicine, some patients may experience mild to moderate adverse reactions, which generally do not require discontinuation of the drug or only require short-term discontinuation or symptomatic treatment for relief. In 1416 clinical studies, no serious adverse reactions were observed. Occasionally (incidence rate of 0.5%), patients may experience dizziness, rash, abdominal distension, sleep disorders, as well as abnormalities in hemoglobin and white blood cell counts, increased total bilirubin and aminotransferase levels, and decreased platelet counts. In very rare cases (incidence rate of 0.1%), patients may experience headaches, nausea, gastric discomfort, and transient increases in blood glucose and serum creatinine levels. Corresponding measures should be taken based on specific clinical situations.

Contraindications
This product is contraindicated for patients who are allergic to it or any of its components.

Precautions
1. During medication, patients' clinical symptoms, signs, and liver function changes should be closely monitored. Follow-up should be enhanced even after the end of the treatment course.
2. For patients with hepatic decompensation, such as significantly elevated bilirubin levels, hypoalbuminemia, cirrhotic ascites, esophageal variceal bleeding, hepatic encephalopathy, and severe organic lesions of the heart, brain, and kidneys, as well as bone marrow suppression, medical advice should be strictly followed.
3. The optimal dose for children under 12 years old should be determined by a physician.
4. There is no research data on the use of this product in pregnant and lactating women. As with other drugs, the risks and benefits should be weighed, and it should be used with caution.
5. The optimal dose for elderly patients over 70 years old has not been determined.

Drug Interactions
There is no research data on drug interactions with other medications.

Pharmacological Effects
Bicyclol is a derivative of the biphenyl structure. Animal studies have found that bicyclol has a lowering effect on elevated aminotransferase levels in acute liver injury induced by carbon tetrachloride, D-galactosamine, and paracetamol in mice, as well as in mouse immune hepatitis. It also alleviates histopathological damage to liver tissue to varying degrees. In vitro studies have shown that bicyclol inhibits the secretion of HBeAg, HBV DNA, and HBsAg in 2.2.15 cell lines of hepatocellular carcinoma cells transfected with human hepatitis B virus.

Storage
Store in a sealed container.

Specification
25mg

Packaging Specification
Aluminum-plastic blister packaging, 9 tablets per board, 2 boards per box.

Expiration
36 months