复方青黛丸, Fufang Qingdai Wan

Drug Name
Fufang Qingdai Wan (Compound Indigo Pill)

Ingredients
Indigo Naturalis, Dark Plum, Taraxacum, Lithospermum, Angelica Dahurica, Salviae Miltiorrhizae Radix, Dictamnus Dasycarpus, Fermented Mass of Medicinal Herbs, Dryopteris Crassirhizoma, Smilacis Glabrae Rhizoma, Portulaca Oleracea, Dioscoreae Septemlobae Rhizoma, Crataegi Fructus Carbonisatus, Schisandrae Chinensis Fructus (Steamed with Wine).

Properties
This medicine is presented as dark blue coated water pills; after removing the coating, it appears grayish-brown, with a slight odor and a slightly bitter and sour taste.

Indications
To clear heat, nourish the blood, detoxify, and eliminate spots. It is used for psoriasis and blood-wind sores caused by blood heat, manifested by bright red rash, obvious sieve-like bleeding, excessive scales, and significant itchiness; or circular or oval red plaques with dandruff-like scales attached, including the mother patch; and for the progressive stage of psoriasis and pityriasis rosea with the above symptoms.

Specification
Each bag contains 6 grams.

Dosage and Administration
Oral administration. Take 1 bag each time, 3 times a day.

Adverse Reactions
(1) Digestive system: mainly diarrhea, abdominal pain, nausea, vomiting, hyperphagia, abnormal liver biochemical indicators, drug-induced liver injury, and severe cases may experience gastrointestinal bleeding.
(2) Skin and its appendages: rash, itchiness, and individual cases of exfoliative dermatitis have been reported.
(3) Hematopoietic system: leukopenia.
(4) Nervous system: dizziness, headache, etc.

Contraindications
(1) Prohibited for those allergic to this medicine.
(2) Prohibited for pregnant women.
(3) Prohibited for those with abnormal liver biochemical indicators, peptic ulcer, or low white blood cell count.

Precautions
(1) This medicine has a cold nature, so it should be used with caution in those with spleen-stomach yang deficiency, gastrointestinal discomfort, and weak constitution.
(2) Avoid tobacco, alcohol, spicy, and greasy foods during medication.
(3) Currently, there is no research data on the use of this medicine in children and lactating women, so it should be used with caution.
(4) Monitor liver biochemical indicators, blood counts, and clinical manifestations during medication. If abnormal liver biochemical indicators, leukopenia, hematochezia, severe abdominal pain, diarrhea, etc., occur, immediately discontinue the medicine and seek medical attention.

Pharmacology and Toxicology
(1) It significantly inhibits the mitosis of vaginal epithelial cells in experimental psoriasis animal models and significantly increases the formation of granular layers in tail scales, indicating that this medicine can normalize epidermal parakeratosis.
(2) It has anti-inflammatory, analgesic, and antipruritic effects.
(3) It promotes blood circulation to remove blood stasis and enhances the adrenal cortical function in animals with kidney yang deficiency.
(4) It significantly reduces the level of C-myc in keratinocytes.
(5) It significantly inhibits the proliferation of colo-16 cells, suggesting that this medicine acts on an important aspect of epidermal cell proliferation in psoriasis.
(6) Under SEM, the submicroscopic structure recovers significantly, suggesting that this medicine has the effect of restoring cell surface membrane glycoproteins.

Storage
Seal tightly and protect from moisture.

Packaging
Biaxially Oriented Polypropylene/Aluminum-coated Polypropylene. 9 bags per box.

Expiration
36 months.