Oral Administration of Xiaojin Pills Combined with Drug Injection for Treating Penile Induration in 28 Cases

Objective  
To observe the clinical efficacy of Xiaojin Pills oral administration combined with drug injection in the treatment of penile induration.

Methods
56 cases were selected and randomly divided into the observation group and the control group,28 casesin each group. The control group was treated by nodal injections of Compound Betamethasone Injection; based on the above treatment，the observation group was added with oral administration of Xiaojin Pills. After 4 weeks of treatment, the clinical efficacy and treatment — related adverse reactions were evaluated;3 months and 12 months after the end of treatment,the pain to the penis, penis bending, penile erectile dysfunction and sexual ability improvement were self -evaluated by the patients. 

Results 
The total effective rate ofthe observation group was 85.71%，which was higher than 64. 29% of the control group (P < 0. 05). The occurrence rates of adverse reactions in the two groups had no statistically significant difference (P > 0.05). Partial bleeder and hematoma in the patients were all mild，can be self—healed and did not need special treatment; swelling and itching were relieved after stopping taking medication. 3 months after the end of treatment, the pain in the penis, penis bending, self — evaluation of penile erectile dysfunction, sexual ability in the observation group were superior to the control group (P < 0.05) ;12 months after the end of treatment,the self - evaluation of penile erectile dysfunction and sexual ability in the observation group were superior to the control group (P < 0.05).

Conclusion
Oral'administration of Xiaojin Pills combined with Compound Betamethasone Injection in treating patients with penile induration is simple，safe, has certain clinical efficacy,can ease the patient’s clinical symptoms and pains, which is worthy of clinical promotion.

Key words: Xiaojin Pills compound betamethasone ; penileinduration; clinical efficacy ; safety